Next »
Tzu Chi Medical Journal
Volume 20, Issue 1
, Pages 1-10
, March 2008
Role of Purinergic and Nicotinic Receptors in the Hypoxia/Hypercapnia Evoked Excitation of Parasympathetic Cardiac Vagal Neurons in the Brainstem
References
-
.
Respiratory variations of the heart rate II–the central mechanism of the respiratory sinus arrhythmia and the inter-relations between the central and the reflex mechanisms
.
Proc Royal Soc
. 1936;119:218–232
- . Synaptic mechanisms involved in the inspiratory modulation of vagal cardio-inhibitory neurones in the cat . J Physiol . 1984;356:65–78
- . Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats: implications for sudden infant death syndrome . J Neurosci . 2004;24:9261–9268
- . Respira tory sinus arrhythmia: endogenous activation of nicotinic receptors mediates respiratory modulation of brainstem cardioinhibitory parasympathetic neurons . Circ Res . 2003;93:565–572
- . Hypoxic apnea and gasping . J Clin Invest . 1975;56:1371–1377
- . Failure of autoresuscitation in weanling mice: significance of cardiac glycogen and heart rate regulation . J Appl Physiol . 1999;87:203–210
- . The cardiorespiratory response to anoxia: normal development and the effect of nicotine . Respir Physiol . 1997;109:231–239
-
.
Nervous control of heart rate: activity in the cardiac vagus of the dogfish
.
J Appl Physiol
. 1982;53:1330–1335
-
Anderson RN. Deaths: leading causes for 2000. National Vital Statistics Reports 2002:50.
- . Prenatal exposure to nicotine impairs protective responses of rat pups to hypoxia in an age-dependent manner . Respir Physiol . 2001;127:61–73
- . Cardiorespiratory recordings from infants dying suddenly and unexpectedly at home . Pediatrics . 1994;93:44–49
- Brainstem 3H-nicotine receptor binding in the sudden infant death syndrome . J Neuropathol Exp Neurol . 1998;57:1018–1025
- . Gasping and other cardiorespiratory patterns during sudden infant deaths . Pediatr Res . 1999;45:350–354
- . Frequency and timing of recurrent events in infants using home cardiorespiratory monitors . J Pediatr . 1998;132:783–789
- . Diminished respiratory sinus arrhythmia in asphyxiated term infants . Am J Obstet Gynecol . 1986;155:1263–1266
- . Finding the failure mechanism in sudden infant death syndrome . Nat Med . 1998;4:157–158
- Dynamic analysis of cardiac R-R intervals in normal infants and in infants who subsequently succumbed to the sudden infant death syndrome . Pediatr Res . 1992;31:606–612
- . Cardiorespiratory interactions in heart-rate control . Ann N Y Acad Sci . 1988;533:350–357
- Smoking and the sudden infant death syndrome . Pediatrics . 1993;91:893–896
- . Cigarette smoking as a risk factor for sudden infant death syndrome: a population-based study . Am J Public Health . 1990;80:29–32
- . Effects of autonomic blockade on the baroreflex in man at rest and during exercise . Circ Res . 1972;30:177–185
- . Reflex control of heart rate in the unanesthetized dog . Am J Physiol . 1970;218:780–789
- . Reflex discharge patterns of cardiac vagal efferent fibres . J Physiol . 1972;222:1–15
- . Arterial baroreflex control of heart rate in the conscious rat . Am J Physiol . 1980;238:H515–H520
- . Autonomic nervous system control of heart rate during baroreceptor activation in conscious and anesthetized rats . J Auton Nerv Syst . 1987;20:121–127
- . Neural organisation and control of the baroreceptor reflex . Rev Physiol Biochem Pharmacol . 1981;88:24–124
-
.
Autonomic control of cardiac pacemaker activity and atrioventricular transmission
.
J Appl Physiol
. 1969;27:465–470
- . Identification and dissociation of cardiovascular neurons from the medulla for patch clamp analysis . Neurosci Lett . 1991;132:217–221
- . Firing properties of identified parasympathetic cardiac neurons in nucleus ambiguus . Am J Physiol . 1996;271:H2609–H2614
- . Voltage-gated currents in identified parasympathetic cardiac neurons in the nucleus ambiguus . Brain Res . 1996;739:258–262
-
.
Advances in parasympathetic control of heart rate and cardiac function
.
News Physiol Sci
. 1999;14:155–161
-
.
Brainstem premotor cardiac vagal neurons
.
In:
Nae Dun BM
, Paul Pilowsky
editor.
Neural Mechanisms of Cardiovascular Regulation
. Dordrecht, The Netherlands: Kluwer Academic Publishers; 2004;p. 371–397
-
.
Central nervous system regulation of the heart
.
In:
Armour JLA Andrew
editors.
Basic and Clinical Neurocardiology
. Oxford University Press; 2004;p. 187–219
- . Acetylcholine activates a nicotinic receptor and an inward current in dorsal motor nucleus of the vagus neurons in vitro . Neurosci Lett . 1995;195:163–166
- . Sensory afferent neuro-transmission in caudal nucleus tractus solitarius–common denominators . Chem Senses . 1996;21:387–395
- . Nicotine excites cardiac vagal neurons via three sites of action . Clin Exp Pharmacol Physiol . 1998;25:453–456
- . Stimulation of NTS activates NMDA and non-NMDA receptors in rat cardiac vagal neurons in the nucleus ambiguus . Brain Res . 1998;792:277–282
- . Nicotine enhances presynaptic and postsynaptic glutamatergic neurotransmission to activate cardiac parasympathetic neurons . Circ Res . 1998;83:1241–1247
- . Superior laryngeal neurons directly excite cardiac vagal neurons within the nucleus ambiguus . Brain Res Bull . 2000;51:135–138
- . Firing properties of identified superior laryngeal neurons in the nucleus ambiguus in the rat . Neurosci Lett . 2001;303:1–4
- . Characteristics of spontaneous and evoked GABAergic synaptic currents in cardiac vagal neurons in rats . Brain Res . 2001;889:78–83
- . Activity of cardiorespiratory networks revealed by transsynaptic virus expressing GFP . J Neurophysiol . 2001;85:435–438
- . Agatoxin-IVA-sensitive calcium channels mediate the presynaptic and postsynaptic nicotinic activation of cardiac vagal neurons . J Neurophysiol . 2001;85:164–168
- Synaptic and neurotransmitter activation of cardiac vagal neurons in the nucleus ambiguus . Ann N Y Acad Sci . 2001;940:237–246
- . Arginine vasopressin enhances GABAergic inhibition of cardiac parasympathetic neurons in the nucleus ambiguus . Neuroscience . 2002;111:699–705
- . Endomorphin-2 inhibits GABAergic inputs to cardiac parasympathetic neurons in the nucleus ambiguus . Neuroscience . 2002;113:975–983
- Ketamine inhibits presynaptic and postsynaptic nicotinic excitation of identified cardiac parasympathetic neurons in nucleus ambiguus . Anesthesiology . 2002;96:667–674
- . Ketamine inhibits sodium currents in identified cardiac parasympathetic neurons in nucleus ambiguus . Anesthesiology . 2002;96:659–666
- . Nociceptin inhibits gamma-aminobutyric acidergic inputs to cardiac parasympathetic neurons in the nucleus ambiguus . J Pharmacol Exp Ther . 2002;300:78–82
- Pentobarbital enhances GABAergic neurotransmission to cardiac parasympathetic neurons, which is prevented by expression of GABAA epsilon subunit . Anesthesiology . 2002;97:717–724
- . Distribution of mu-opioid receptors in rat visceral premotor neurons . Neuroscience . 2002;115:851–860
- Mu-opioid receptors are located postsynaptically and endomorphin-1 inhibits voltage-gated calcium currents in premotor cardiac parasympathetic neurons in the rat nucleus ambiguus . Neuroscience . 2003;116:573–582
- . Synaptic activation of cardiac vagal neurons by capsaicin sensitive and insensitive sensory neurons . Brain Res . 2003;979:210–215
- Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons . J Neurophysiol . 2003;89:2473–2481
- . Glycinergic inputs to cardiac vagal neurons in the nucleus ambiguus are inhibited by nociceptin and muselective opioids . J Neurophysiol . 2003;90:1581–1588
- Fentanyl inhibits GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus . Brain Res . 2004;1007:109–115
-
.
Respiratory variations of the heart rate II–the central mechanism of the respiratory arrhythmia and the interrelationships between the central and reflex mechanisms
.
Proc Roy Soc
. 1935;119:218–231
- . Some reflex cardioinhibitory responses in the cat and their modulation by central inspiratory neuronal activity . J Physiol . 1991;439:559–577
- . Effects of respiration on blood pressure and heart rate variability in humans . Clin Exp Pharmacol Physiol . 1991;18:735–742
- . Quantitative respiratory sinus arrhythmia analysis. A simple noninvasive, reimbursable measure of cardiac wellness and dysfunction . Ann N Y Acad Sci . 1991;618:67–101
- . Respiratory sinus arrhythmia in dogs. Effects of phasic afferents and chemostimulation . J Clin Invest . 1991;87:1621–1627
- . Power spectral analysis of heart rate variability in traumatic quadriplegic humans . Am J Physiol . 1990;258:H1722–H1726
- . Beat-bybeat modulation of AV conduction. II. Autonomic neural mechanisms . Am J Physiol . 1986;251:H1134–H1142
- . The baroreceptor input to cardiac vagal motoneurones . J Physiol . 1978;282:365–374
- . Breathing: rhythmicity, plasticity, chemosensitivity . Annu Rev Neurosci . 2003;26:239–266
- . Reconfiguration of the neural network controlling multiple breathing patterns: eupnea, sighs and gasps [see comment] . Nat Neurosci . 2000;3:600–607
- . Clinical correlates, natural history and outcome of neonatal apnoea . Semin Neonatol . 2004;9:205–211
- Absence of bradycardic response to apnea and hypoxia in heart transplant recipients with obstructive sleep apnea . J Heart Lung Transplant . 1997;16:394–397
- . Profound reflex bradycardia produced by transient hypoxia or hypercapnia in man . Eur Surg Res . 1977;9:75–84
- . Parasympathetic hyperresponsiveness and bradyarrhythmias during apnoea in hypertension . Clin Auton Res . 1992;2:171–176
- . Apnoea of prematurity . Paediatr Respir Rev . 2004;5(Suppl A):S377–S382
- . Cardiovascular responses to autonomic blockade in hypoxemic fetal lambs . Biol Neonate . 1980;37:233–242
- . The effect of fetal heart rate on cardiovascular function during hypoxemia . Am J Obstet Gynecol . 1980;138:1190–1199
- . Circulatory responses to acute hypoxia in spontaneously hypertensive and normotensive rats . Acta Physiol Pol . 1980;31:463–468
- . Effects on hypoxaemia on foetal heart rate, variability and cardiac rhythm . Clin Exp Pharmacol Physiol . 1998;25:577–584
- . Effect of acute hypoxemia and respiratory acidosis on the fetal heart rate in monkeys . Am J Obstet Gynecol . 1981;141:797–806
- . Hypoxic tachycardia in hypoxiaacclimated rats . Jpn J Physiol . 1982;32:149–152
- . Effects of hypoxia on cardiac vagal efferent activity and on the action of the vagus nerve at the heart in the dog . J Auton Nerv Syst . 1986;17:325–329
- . Abnormal heart rate response to hypercapnia in boys with an apparent life-threatening event . Acta Paediatr . 2002;91:1318–1323
- . Cardiovascular responses to hypoxia in the spontaneously breathing cat: reflexes originating from carotid and aortic bodies . Arch Biol Med Exp (Santiago) . 1983;16:29–41
- . Hypoxia inhibits baroreflex vagal bradycardia via a central action in anaesthetized rats . Exp Physiol . 1999;84:47–56
- . Abolition of hypoxic vagal bradycardia by lateral mesencephalic lesions in spinal cats . Am J Physiol . 1979;237:R15–R19
- . Failure of autoresuscitation in weanling mice: significance of cardiac glycogen and heart rate regulation . J Appl Physiol . 1999;87:203–210
- . The cardiorespiratory response to anoxia: normal development and the effect of nicotine . Respir Physiol . 1997;109:231–239
- . Sleep-induced apnea syndrome. Prevalence of cardiac arrhythmias and their re versal after tracheostomy . Am J Med . 1977;63:348–358
- . Nicotine and cotinine levels in pericardial fluid in victims of SIDS . Acta Paediatr . 1994;83:59–62
- . Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality . Brain Res Dev Brain Res . 1999;113:1–12
- . Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: implications for perinatal morbidity and mortality, and for sudden infant death syndrome . Teratology . 1997;55:177–184
- . The alpha4beta2 agonist SIB 1765F, but not the alpha7 agonist AR-R 17779, cross-sensitises to the psychostimulant effects of nicotine . Psychopharmacology (Berl) . 2000;150:233–236
- . Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine . Br J Pharmacol . 1995;114:454–460
- . The putative role of extra-synaptic mesolimbic dopamine in the neurobiology of nicotine dependence . Behav Brain Res . 2000;113:73–83
-
.
Chronic exposure to nicotine upregulates the human (alpha)4(beta)2 nicotinic acetylcholine receptor function
.
J Neurosci
. 2001;21:1819–1829
- . Prenatal nicotine exposure alters the types of nicotinic receptors that facilitate excitatory inputs to cardiac vagal neurons . J Neurophysiol . 2004;92:2548–2554
- . Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes . J Pharmacol Exp Ther . 1993;265:1455–1473
- . Neural mechanisms generating respiratory pattern in mammalian brain stem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity . J Neurophysiol . 1990;64:1149–1169
- . Respiratory rhythm generation in the in vitro brain stem–spinal cord preparation of the neonatal rat . J Physiol . 1984;354:173–183
- Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice . J Physiol . 2002;538:957–973
- . Effect of nicotine exposure on postnatal ventilatory responses to hypoxia and hypercapnia . Respir Physiol . 1996;106:1–11
- . Deficient hypoxia awakening response in infants of smoking mothers: possible relationship to sudden infant death syndrome . J Pediatr . 1995;127:691–699
- . Respiratory plasticity: differential actions of continuous and episodic hypoxia and hypercapnia . Respir Physiol . 2001;129:25–35
- Invited review: intermittent hypoxia and respiratory plasticity . J Appl Physiol . 2001;90:2466–2475
- . Sleep apneas: an oxidative stress? . Am J Respir Crit Care Med . 2002;165:859–860
- . Increased injury following intermittent fetal hypoxia– reoxygenation is associated with increased free radical production in fetal rabbit brain . J Neuropathol Exp Neurol . 1999;58:972–981
- . Redox signaling in central neural regulation of cardiovascular function . Prog Biophys Mol Biol . 2004;84:125–149
- . Reactive oxygen species stimulate central and peripheral sympathetic nervous system activity . Am J Physiol Heart Circ Physiol . 2004;287:H695–H703
- . Tempol lowers blood pressure and sympathetic nerve activity but not vascular Oin DOCA-salt rats . Hypertension . 2004;43:329–334
- . Hydrogen peroxide increases the activity of rat sympathetic preganglionic neurons in vivo and in vitro . Neuroscience . 2003;121:641–647
- . Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats . Circulation . 2004;109:2357–2362
- . Altered production of nitric oxide and reactive oxygen species in rat nodose ganglion neurons during acute hypoxia . Brain Res . 2003;961:1–9
-
.
Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress
.
J Neurosci
. 1999;19:9209–9217
- . Iron toxicity in organotypic cultures of hippocampal slices: role of reactive oxygen species . J Neurochem . 2003;85:492–502
PII: S1016-3190(08)60001-4
doi: 10.1016/S1016-3190(08)60001-4
© 2008 Buddhist Compassion Relief Tzu Chi Foundation. Published by Elsevier Inc. All rights reserved.
Next »
Tzu Chi Medical Journal
Volume 20, Issue 1
, Pages 1-10
, March 2008
