« Previous
Next »
Tzu Chi Medical Journal
Volume 20, Issue 4
, Pages 280-285
, December 2008
The Neuroprotection of Kappa Opioid Receptor Agonist BRL52537 is Partly Through Enhancing Endogenous GABA Function
References
- . Treatment of stroke with opiate antagonists–effects of exogenous antagonists and dynorphin 1-13 . Neuropeptides . 1985;5:307–310
- . Opioid peptide levels in gerbil brain after transient ischemia: lasting depletion of hippocampal dynorphin . Stroke . 1987;18:765–770
- . Reversal of induced ischemic neurologic deficit in gerbils by the opiate antagonist naloxone . Science . 1982;215:69–71
- Naloxone therapy during focal cerebral ischemia evaluation in a primate model . Stroke . 1984;15:621–627
- Evaluation of delayed treatment of focal cerebral ischemia with three selective kappa-opioid agonists in cats . Stroke . 1994;25:2047–2054
- Neuroprotective actions of GR89696, a highly potent and selective kappa-opioid receptor agonist . Br J Pharmacol . 1991;103:1819–1823
- . Effect of the kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat . Brain Res . 1993;629:10–18
- . Evaluation of neuroprotection and behavioral recovery by the kappa-opioid, PD117302 following transient forebrain ischemia . Brain Res Bull . 1994;34:111–116
- . U-50,488H, a kappa-opioid receptor agonist, markedly prevents memory dysfunctions induced by transient cerebral ischemia in mice . Brain Res . 1993;619:223–228
- . Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion . Stroke . 1990;21:1727–1733
- Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia . Brain Res . 1992;579:309–314
- Elevation of neuroactive substances in the cortex of cats during prolonged focal ischemia . J Cereb Blood Flow Metab . 1993;13:586–594
- Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology . J Cereb Blood Flow Metab . 1993;13:575–585
- Extracellular glutamate during focal cerebral ischaemia in rats: time course and calcium dependency . J Neurochem . 1994;63:1003–1011
- . Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury? . J Neurotrauma . 1997;14:677–698
- . A dendritic GABAA-mediated IPSP regulates facilitation of NMDA-mediated responses to burst stimulation of afferent fibers in piriform cortex . J Neurosci . 1996;16:307–312
- . Chlormethiazole antagonises seizures induced by N-methyl-DL-aspartate without interacting with the NMDA receptor complex . Psychopharmacology (Berl) . 1993;112:403–406
- Muscimol prevents neuronal injury induced by NMDA . Jpn J Pharmacol . 1994;64:125–128
- . Chlormethiazole attenuates the derangement of sensory evoked potential (SEP) induced by ICV administration of NMDA . Psychopharmacology (Berl) . 1993;111:256–258
- Kappa-opioid receptor selectivity for ischemic neuroprotection with BRL 52537 in rats . Anesth Analg . 2003;97:1776–1783
- Prolonged opportunity for ischemic neuroprotection with selective kappa-opioid receptor agonist in rats . Stroke . 2004;35:1180–1185
- Ischemic neuroprotection with selective kappa-opioid receptor agonist is gender specific . Stroke . 2005;36:1557–1561
- . Kappa1- and kappa2-opioid receptors mediating presynaptic inhibition of dopamine and acetylcholine release in rat neostriatum . Br J Pharmacol . 1997;122:520–524
- . Modulation of the behavioral and neurochemical effects of psychostimulants by kappa-opioid receptor systems . Ann N Y Acad Sci . 2001;937:50–73
- . Modulation of neurotransmitter release in the basal ganglia of the rat brain by dynorphin peptides . J Pharmacol Exp Ther . 1999;290:1307–1315
- Neuroprotective kappaopioid receptor agonist BRL 52537 attenuates ischemiaevoked nitric oxide production in vivo in rats . Stroke . 2003;34:1533–1538
- . Kappa opioid receptor activation in the nucleus accumbens inhibits glutamate and GABA release through different mechanisms . J Neurophysiol . 2003;89:2389–2395
- . GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke . Neuropharmacology . 2000;39:1483–1494
- . Gamma-aminobutyric acid(A) neurotransmission and cerebral ischemia . J Neurochem . 2001;77:353–371
- Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat . J Neurochem . 1991;57:470–478
- . Postischemic in hibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus . Hippocampus . 1995;5:460–468
- . Characterization of glutamate, aspartate, and GABA release from ischemic rat cerebral cortex . Brain Res Bull . 1994;34:457–466
- Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum . J Neurosci . 1995;15:529–539
- Progressive decrease in extracellular GABA concentrations in the post-ischemic period in the striatum: a microdialysis study . Brain Res . 1994;666:99–103
PII: S1016-3190(08)60051-8
doi: 10.1016/S1016-3190(08)60051-8
© 2008 Buddhist Compassion Relief Tzu Chi Foundation. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Tzu Chi Medical Journal
Volume 20, Issue 4
, Pages 280-285
, December 2008
