Tzu Chi Medical Journal
Volume 21, Issue 1 , Pages 66-69, March 2009

Incidence of Alloantibodies in Transfused Patients in Eastern Taiwan

  • Rong-Hwa Jan

      Affiliations

    • Institute of Medical Science, Tzu Chi University, Hualien, Taiwan
    • Department of Pediatrics, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    • ,
  • Li-Chih Yu

      Affiliations

    • Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    • ,
  • Shu-Hui Wen

      Affiliations

    • Institute of Public Health, College of Medicine, Tzu Chi University, Hualien, Taiwan
    • ,
  • Shii-Shou Tsai

      Affiliations

    • Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    • ,
  • Teng-Yi Lin

      Affiliations

    • Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, 707, Section 3, Chung-Yang Road, Hualien, Taiwan

Received 10 January 2008; received in revised form 4 February 2008; accepted 16 July 2008.

Abstract 

Objective

The study was conducted to determine the prevalence of red blood cell alloantibodies for transfused patients in the East Taiwanese population.

Materials and Methods

We analyzed the clinical and transfusion records of 15,794 individuals who received transfusions in Hualien Tzu Chi Hospital from 2004 to 2006. Blood samples were subjected to standard blood bank procedures for screening for antibodies.

Results

Of the 15,794 transfused patients, 538 patients (3.39%) were found to have alloantibodies. Among these 538 patients, 333 patients were found to carry alloantibodies at the initial transfusion (2.0%) and 205 (1.3%) patients developed alloantibodies during the transfusion period.

Conclusion

Our data demonstrate that anti-Mia was the most frequently detected alloantibody in the Eastern Taiwanese population, with an incidence (1.5%) that was higher than reported in other Taiwanese populations.

Keywords:  Alloantibodies , Anti-Mia , Transfusion

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PII: S1016-3190(09)60010-0

doi:10.1016/S1016-3190(09)60010-0

Tzu Chi Medical Journal
Volume 21, Issue 1 , Pages 66-69, March 2009

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