Tzu Chi Medical Journal
Volume 21, Issue 2 , Pages 161-164, June 2009

Short Stature Without Neurological Manifestations in a Child with a Suprasellar Tumor

  • Kun-Shan Cheng

      Affiliations

    • Department of Pediatrics, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan
  • ,
  • Nan-Chang Chiu

      Affiliations

    • Department of Pediatrics, Taipei Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Jon-Kway Huang

      Affiliations

    • Department of Radiology, Taipei Mackay Memorial Hospital, Taipei, Taiwan
  • ,
  • Yann-Jinn Lee

      Affiliations

    • Department of Pediatrics, Taipei Mackay Memorial Hospital, Taipei, Taiwan
    • Department of Medical Research, Taipei Mackay Memorial Hospital, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Pediatrics, Mackay Memorial Hospital, 92, Section 2, Chung-Shan North Road, Taipei, Taiwan

Received 14 July 2008; received in revised form 14 August 2008; accepted 24 December 2008.

Abstract 

Addressing the problem of short stature in pediatrics is challenging because normal somatic growth depends on a complex interaction between genetic, nutritional, and hormonal factors. We report a 14-year-old girl with deceleration of growth velocity and delayed puberty but no other discernible neurologic or ophthalmologic symptoms or signs. Clonidine and insulin tolerance tests confirmed growth hormone deficiency, and magnetic resonance imaging disclosed a suprasellar mass. This case demonstrates that growth failure may be the only early sign of suprasellar tumor. Rigorous pursuit of the cause of a growth disorder should thus be considered, as it may disclose a potentially serious but treatable condition.

Keywords:  Growth hormone deficiency , Short stature , Suprasellar tumor

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PII: S1016-3190(09)60030-6

doi:10.1016/S1016-3190(09)60030-6

Tzu Chi Medical Journal
Volume 21, Issue 2 , Pages 161-164, June 2009