Tzu Chi Medical Journal
Volume 21, Issue 3 , Pages 204-209 , September 2009

Should Tonsillar Carcinoma With Nasopharynx Invasion Alone be Classified as a T4b Disease?

  • Moon-Sing Lee

      Affiliations

    • Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
    • School of Medicine, Tzu Chi University, Hualien, Taiwan
  • ,
  • Yee-Min Jen

      Affiliations

    • Department of Radiation Oncology, Tri-Service General Hospital, Taipei, Taiwan
  • ,
  • Dai-Wei Liu

      Affiliations

    • School of Medicine, Tzu Chi University, Hualien, Taiwan
    • Department of Radiation Oncology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
  • ,
  • Yu-Chieh Su

      Affiliations

    • School of Medicine, Tzu Chi University, Hualien, Taiwan
    • Division of Hematology-Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
  • ,
  • Shih-Kai Hung

      Affiliations

    • Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
    • School of Medicine, Tzu Chi University, Hualien, Taiwan
  • ,
  • Jing-Min Hwang

      Affiliations

    • School of Medicine, Tzu Chi University, Hualien, Taiwan
    • Department of Radiation Oncology, Buddhist Tzu Chi General Hospital, Taipei Branch, Taiwan
  • ,
  • Ching-Chih Lee

      Affiliations

    • Department of Otolaryngology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
  • ,
  • Szu-Chi Li

      Affiliations

    • Division of Hematology-Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
  • ,
  • Wei-Ta Tsai

      Affiliations

    • Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
  • ,
  • Fong-Ling Chen

      Affiliations

    • Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
  • ,
  • Hon-Yi Lin

      Affiliations

    • Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan
    • School of Medicine, Tzu Chi University, Hualien, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Buddhist Dalin Tzu Chi General Hospital, 2, Min-Sheng Road, Dalin, Chiayi, Taiwan

Received 11 November 2008 ,Revised 15 December 2008 ,Accepted 19 February 2009.

References 

  1. National Comprehensive Cancer Network  . National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Head and Neck Cancers, Version 2, 2008 . Available from http://www.nccn.org/professionals/physician_gls/PDF/head-and-neck.pdf [Date accessed: January 5, 2009]
  2. Adelstein DJ , Li Y , Adams GL , et al.   An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer . J Clin Oncol . 2003;21:92–98
  3. Fallai C , Bolner A , Signor M , et al.   Long-term results of conventional radiotherapy versus accelerated hyperfractionated radiotherapy versus concomitant radiotherapy and chemotherapy in locoregionally advanced carcinoma of the oropharynx . Tumori . 2006;92:41–54
  4. In:  Greene FL ,  Page DL ,  Fleming ID , et al. editor. American Joint Committee on Cancer Staging Manual . 6th edition. Philadelphia: Springer; 2002;p. 27–39
  5. In:  Greene FL ,  Compton CC ,  Fritz AG ,  Shan JP ,  Winchester DP editor. American Joint Committee on Cancer (AJCC)– Cancer Staging Atlas . 7th edition. New York: Springer Science + Business Media; 2006;p. 27–39
  6. Bensadoun RJ , Benezery K , Dassonville O , et al.   French multicenter phase III randomized study testing concurrent twice-a-day radiotherapy and cisplatin/5-fluorouracil chemotherapy (BiRCF) in unresectable pharyngeal carcinoma: results at 2 years (FNCLCC-GORTEC) . Int J Radiat Oncol Biol Phys . 2006;64:983–994
  7. Chao KS , Ozyigit G , Blanco AI , et al.   Intensity-modulated radiation therapy for oropharyngeal carcinoma: impact of tumor volume . Int J Radiat Oncol Biol Phys . 2004;59:43–50
  8. Lee WR , Mendenhall WM , Parsons JT , Million RR , Cassisi NJ , Stringer SP . Carcinoma of the tonsillar region: a multivariate analysis of 243 patients treated with radical radiotherapy . Head Neck . 1993;15:283–288
  9. Lin HY , Jen YM , Liu DW , et al.   The role of primary surgery in resectable stage III/IV tonsillar carcinoma . Tzu Chi Med J . 2008;20:49–57
  10. Brizel DM , Albers ME , Fisher SR , et al.   Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer . N Engl J Med . 1998;338:1798–1804

PII: S1016-3190(09)60040-9

doi: 10.1016/S1016-3190(09)60040-9

Tzu Chi Medical Journal
Volume 21, Issue 3 , Pages 204-209 , September 2009