Tzu Chi Medical Journal
Volume 22, Issue 2 , Pages 103-105, June 2010

Malakoplakia of Ipsilateral Kidney, Ureter and Bladder

  • Yung-Chih Chen
    • ,
  • Hann-Chorng Kuo

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Urology, Buddhist Tzu Chi General Hospital, 707, Section 3, Chung-Yang Road, Hualien, Taiwan

Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan

Received 17 April 2009; received in revised form 21 April 2009; accepted 5 May 2009.

Article Outline

Abstract 

Malakoplakia is a rare chronic inflammatory disease of the urinary tract, usually caused by Escherichia coli infection. We report a 75-year-old woman who presented with hydronephrosis and pyuria associated with E. coli infection. Abdominal computed tomography revealed several renal stones and severe hydronephrosis of the right kidney. Biopsies of the urinary bladder and ureter revealed erosion and acute inflammation. According to a culture sensitivity test, antimicrobial treatment was prescribed with cephradine 500 mg every 6 hours and amoxicillin-clavulanic acid 100 mg twice daily for 1 month. Because of the advanced hydronephrosis with impaired renal function, a right nephroureterectomy was performed. Malakoplakia of the right kidney, ureter and urinary bladder was confirmed by pathology with Michaelis-Gutmann bodies present in the surgical specimen. The patient tolerated the operation well. She regained a good health status and was regularly followed-up in the urologic department.

Keywords:  Malakoplakia , Michaelis-Gutmann bodies , Nephrectomy

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References 

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PII: S1016-3190(10)60049-3

doi:10.1016/S1016-3190(10)60049-3

Tzu Chi Medical Journal
Volume 22, Issue 2 , Pages 103-105, June 2010

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